Lost in plasmids: next generation sequencing and the complex genome of the tick-borne pathogen Borrelia burgdorferi

Lost in plasmids: next generation sequencing and the complex genome of the tick-borne pathogen Borrelia burgdorferi

Abstract Background Borrelia (B.) burgdorferi sensu lato, including the tick-transmitted agents of human Lyme borreliosis, have particularly complex genomes, consisting of a linear main chromosome and numerous linear and circular plasmids. The number and structure of plasmids is variable even in str...

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Bibliographic Details
Main Authors: G. Margos, S. Hepner, C. Mang, D. Marosevic, S. E. Reynolds, S. Krebs, A. Sing, M. Derdakova, M. A. Reiter, V. Fingerle
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Genomics
Subjects:
Borrelia burgdorferi
Genomics
Plasmids
Next generation sequencing
De novo assembly
Online Access:http://link.springer.com/article/10.1186/s12864-017-3804-5

Internet

http://link.springer.com/article/10.1186/s12864-017-3804-5

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