Role of PITRM1 in Mitochondrial Dysfunction and Neurodegeneration

Role of PITRM1 in Mitochondrial Dysfunction and Neurodegeneration

Mounting evidence shows a link between mitochondrial dysfunction and neurodegenerative disorders, including Alzheimer Disease. Increased oxidative stress, defective mitodynamics, and impaired oxidative phosphorylation leading to decreased ATP production, can determine synaptic dysfunction, apoptosis...

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Bibliographic Details
Main Authors: Dario Brunetti, Alessia Catania, Carlo Viscomi, Michela Deleidi, Laurence A. Bindoff, Daniele Ghezzi, Massimo Zeviani
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomedicines
Subjects:
PITRM1
pitrilysin metallopeptidase 1
mitochondrial proteostasis
Alzheimer Disease
neurodegeneration
neurodegenerative diseases
Online Access:https://www.mdpi.com/2227-9059/9/7/833

Internet

https://www.mdpi.com/2227-9059/9/7/833

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