SQSTM1/p62 Promotes Cell Growth and Triggers Autophagy in Papillary Thyroid Cancer by Regulating the AKT/AMPK/mTOR Signaling Pathway

SQSTM1/p62 Promotes Cell Growth and Triggers Autophagy in Papillary Thyroid Cancer by Regulating the AKT/AMPK/mTOR Signaling Pathway

BackgroundThyroid cancer is one of the most common endocrine malignancies worldwide, and papillary thyroid cancer (PTC) is the most common pathologic type of thyroid cancer. SQSTM1/p62 activity mediates different biological functions. This study aimed to investigate the effect of SQSTM1/p62, a multi...

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Bibliographic Details
Main Authors: Fangqin Yu, Runsheng Ma, Chenguang Liu, Lele Zhang, Kaixiang Feng, Meiqi Wang, Detao Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
SQSTM1/p62
papillary thyroid cancer
proliferation
autophagy
TPC-1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.638701/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.638701/full

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