Benzamides Substituted with Quinoline-Linked 1,2,4-Oxadiazole: Synthesis, Biological Activity and Toxicity to Zebrafish Embryo

Benzamides Substituted with Quinoline-Linked 1,2,4-Oxadiazole: Synthesis, Biological Activity and Toxicity to Zebrafish Embryo

To develop new compounds with high activity, broad spectrum and low-toxicity, 17 benzamides substituted with quinoline-linked 1,2,4-oxadiazole were designed using the splicing principle of active substructures and were synthesized. The biological activities were evaluated against 10 fungi, indicatin...

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Bibliographic Details
Main Authors: Bin-Long Sun, Ying-Ying Wang, Sen Yang, Min-Ting Tu, Ying-Ying Shao, Yi Hua, Yi Zhou, Cheng-Xia Tan
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
quinoline
synthesis
1,2,4-oxadiazole
biological activity
toxicity
Online Access:https://www.mdpi.com/1420-3049/27/12/3946

Internet

https://www.mdpi.com/1420-3049/27/12/3946

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