High concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells
Abstract Endoglin (ENG) is a single-pass transmembrane protein highly expressed on vascular endothelial cells, although low expression levels can be detected in many other cell types. Its extracellular domain can be found in circulation known as soluble endoglin (sENG). Levels of sENG are elevated i...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-04-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-33352-3 |