Enhanced stability and skin permeation of ibuprofen-loaded solid lipid nanoparticles based binary solid lipid matrix: Effect of surfactant and lipid compositions

Enhanced stability and skin permeation of ibuprofen-loaded solid lipid nanoparticles based binary solid lipid matrix: Effect of surfactant and lipid compositions

Hypothesis: The type of emulsifier selected has an impact on the physicochemical properties of solid lipid nanoparticles (SLNs). This study was designed to compare the effects of emulsifiers on the physicochemical properties and in vitro skin performance of SLNs prepared from a binary mixture of Sof...

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Bibliographic Details
Main Authors: Thitirat Chantaburanan, Veerawat Teeranachaideekul, Anchalee Jintapattanakit, Doungdaw Chantasart, Varaporn Buraphacheep Junyaprasert
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Solid lipid nanoparticles
Binary lipid matrix
Long-term stability
In vitro drug release
In vitro skin permeation
Crystallinity, Ibuprofen
Online Access:http://www.sciencedirect.com/science/article/pii/S259015672300049X

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http://www.sciencedirect.com/science/article/pii/S259015672300049X

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