Synthesis, antifungal activity and in vitro mechanism of novel 1-substituted-5-trifluoromethyl-1H-pyrazole-4-carboxamide derivatives

Inspired by the wide application of amides in plant pathogens, a series of novel 1-substituted-5-trifluoromethyl‑1H‑pyrazole-4-carboxamide derivatives were designed and synthesized. Bioassay results indicated that some target compounds exhibited excellent and broad-spectrum in vitro and certain in v...

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Bibliographic Details
Main Authors: Jingxin Yang, Dewen Xie, Chengzhi Zhang, Cailong Zhao, Zhibing Wu, Wei Xue
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535222003033