Preclinical Evaluation of Nitroxide-Functionalised Ciprofloxacin as a Novel Antibiofilm Drug Hybrid for Urinary Tract Infections

Preclinical Evaluation of Nitroxide-Functionalised Ciprofloxacin as a Novel Antibiofilm Drug Hybrid for Urinary Tract Infections

Urinary tract infections (UTIs) are the second most common bacterial infection with high recurrence rates and can involve biofilm formation on patient catheters. Biofilms are inherently tolerant to antimicrobials, making them difficult to eradicate. Many antibiofilm agents alone do not have bacteric...

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Bibliographic Details
Main Authors: Sophia Hawas, Jilong Qin, Sandra Wiedbrauk, Kathryn Fairfull-Smith, Makrina Totsika
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Antibiotics
Subjects:
bladder
urinary tract infection
UPEC
bacterial biofilms
catheters
nitroxides
Online Access:https://www.mdpi.com/2079-6382/12/10/1479

Internet

https://www.mdpi.com/2079-6382/12/10/1479

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