Ursolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer

Ursolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer

ABSTRACT Oxaliplatin is a key drug in chemotherapy of colorectal cancer (CRC). However, its efficacy is unsatisfied due to drug resistance of cancer cells. In this study, we tested whether a natural agent, ursolic acid, was able to enhance the efficacy of oxaliplatin for CRC. Four CRC cell lines inc...

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Bibliographic Details
Main Authors: Jianzhen Shan, Yanyan Xuan, Qi Zhang, Chunpeng Zhu, Zhen Liu, Suzhan Zhang
Format: Article
Language:English
Published: Oxford University Press 2016-07-01
Series:Protein & Cell
Subjects:
ursolic acid
colorectal cancer
oxaliplatin
signaling pathways
Online Access:http://link.springer.com/article/10.1007/s13238-016-0295-0

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http://link.springer.com/article/10.1007/s13238-016-0295-0

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