Tumor-associated macrophages and Tregs influence and represent immune cell infiltration of muscle-invasive bladder cancer and predict prognosis

Abstract Introduction and objective Muscle-invasive urothelial bladder cancer (MIBC) is associated with limited response rates to systemic therapy, risk of recurrence and death. Tumor infiltrating immune cells have been associated with outcome and response to chemo-and immunotherapy in MIBC. We aime...

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Bibliographic Details
Main Authors: Florestan J. Koll, Severine Banek, Luis Kluth, Jens Köllermann, Katrin Bankov, Felix K.-H. Chun, Peter J. Wild, Andreas Weigert, Henning Reis
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-023-03949-3