Characterization of DNA Methylation Associated Gene Regulatory Networks During Stomach Cancer Progression

Characterization of DNA Methylation Associated Gene Regulatory Networks During Stomach Cancer Progression

DNA methylation plays a critical role in tumorigenesis through regulating oncogene activation and tumor suppressor gene silencing. Although extensively analyzed, the implication of DNA methylation in gene regulatory network is less characterized. To address this issue, in this study we performed an...

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Bibliographic Details
Main Authors: Jun Wu, Yunzhao Gu, Yawen Xiao, Chao Xia, Hua Li, Yani Kang, Jielin Sun, Zhifeng Shao, Zongli Lin, Xiaodong Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Genetics
Subjects:
DNA methylation
gene regulation network
stomach cancer
tumor stages
system level
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00711/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00711/full

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