Implications of combined NOD2 and other gene mutations in autoinflammatory diseases

Implications of combined NOD2 and other gene mutations in autoinflammatory diseases

NOD-like receptors (NLRs) are intracellular sensors associated with systemic autoinflammatory diseases (SAIDs). We investigated the largest monocentric cohort of patients with adult-onset SAIDs for coinheritance of low frequency and rare mutations in NOD2 and other autoinflammatory genes. Sixty-thre...

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Bibliographic Details
Main Authors: Hafsa Nomani, Zuoming Deng, Brianne Navetta-Modrov, Jie Yang, Mark Yun, Olga Aroniadis, Peter Gorevic, Ivona Aksentijevich, Qingping Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
Nod2
NLRP3
NLRP12
autoinflammatory
familial Mediterranean fever
digenic
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1265404/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1265404/full

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