Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL[S]

Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL[S]

ApoC-III is often assumed to retard the intravascular processing of triglyceride-rich lipoproteins (TRLs) by inhibiting LPL, but that view is based largely on studies of free LPL. We now recognize that intravascular LPL is neither free nor loosely bound, but instead is tightly bound to glycosylphosp...

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Bibliographic Details
Main Authors: Mikael Larsson, Christopher M. Allan, Rachel S. Jung, Patrick J. Heizer, Anne P. Beigneux, Stephen G. Young, Loren G. Fong
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Journal of Lipid Research
Subjects:
glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
lipoprotein lipase
hypertriglyceridemia
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520339596

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http://www.sciencedirect.com/science/article/pii/S0022227520339596

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