Fibroblast growth factor 2 acts as an upstream regulator of inhibition of pulmonary fibroblast activation

Fibroblast growth factor 2 acts as an upstream regulator of inhibition of pulmonary fibroblast activation

Fibroblast growth factor (FGF) signaling plays a crucial role in lung development and repair. Fibroblast growth factor 2 (FGF2) can inhibit fibrotic gene expression and suppress the differentiation of pulmonary fibroblasts (PFs) into myofibroblasts in vitro, suggesting that FGF2 is a potential targe...

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Bibliographic Details
Main Authors: Xiangqin Tian, Yangyang Jia, Yonglong Guo, Hongyin Liu, Xinhua Cai, Yong Li, Zhuangzhuang Tian, Changye Sun
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:FEBS Open Bio
Subjects:
extracellular matrix
FGF2
mRNA sequencing
pulmonary fibroblasts
α‐SMA
Online Access:https://doi.org/10.1002/2211-5463.13691

Internet

https://doi.org/10.1002/2211-5463.13691

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