Use of Exposure Data to Establish Causality in Drug–Adverse Event Relationships: An Example with Desvenlafaxine

Causality algorithms help establish relationships between drug use and adverse event (AE) occurrence. High drug exposure leads to a higher likelihood of an AE being classified as an adverse drug reaction (ADR). However, there is a knowledge gap regarding what concentrations are predictive of ADRs, a...

Full description

Bibliographic Details
Main Authors: Andrea Rodríguez-Lopez, Gina Mejía-Abril, Pablo Zubiaur, Sofía Calleja, Manuel Román, Francisco Abad-Santos, Dolores Ochoa
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/17/1/69