Roles of PI3K and JAK pathways in viability of retinal ganglion cells after acute elevation of intraocular pressure in rats with different autoimmune backgrounds

<p>Abstract</p> <p>Background</p> <p>We recently showed that whereas inhibition of PI3K/akt or JAK/STAT pathway promoted retinal ganglion cell (RGC) survival after optic nerve (ON) injury in Fischer 344 (F344) rats, the same inhibition resulted in aggravated RGC loss af...

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Bibliographic Details
Main Authors: Wang Ningli, Li Zhiwei, Huang Yao, van Rooijen Nico, Cui Qi
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/9/78