New benzoxazole-based sulphonamide hybrids analogs as potent inhibitors of α-amylase and α-glucosidase: Synthesis and in vitro evaluation along with in silico study

New benzoxazole-based sulphonamide hybrids analogs as potent inhibitors of α-amylase and α-glucosidase: Synthesis and in vitro evaluation along with in silico study

The development of drugs resistance in diabetes mellitus is a growing clinical problem, creates many challenges for patient. To overcome these problems, there is a serious deficiency of anti-diabetic agents, may be synthesized that inhibit alpha amylase and alpha glucosidase activity. Here, we have...

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Bibliographic Details
Main Authors: Shoaib Khan, Fazal Rahim, Wajid Rehman, Mohsan Nawaz, Muhammad Taha, Srosh Fazil, Rafaqat Hussain, Syed Adnan Ali Shah, Magda H. Abdellatif
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Arabian Journal of Chemistry
Subjects:
Benzoxazole
alpha-amylase and alpha-glucosidase
SAR
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535222006578

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http://www.sciencedirect.com/science/article/pii/S1878535222006578

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