Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut

Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut

Anti-inflammatory treatments for gastrointestinal diseases can often have detrimental side effects. Here the authors engineer E. coli Nissle 1917 to create a fibrous matrix that has a protective effect in DSS-induced colitis mice.

Bibliographic Details
Main Authors: Pichet Praveschotinunt, Anna M. Duraj-Thatte, Ilia Gelfat, Franziska Bahl, David B. Chou, Neel S. Joshi
Format: Article
Language:English
Published: Nature Portfolio 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13336-6

Internet

https://doi.org/10.1038/s41467-019-13336-6

Similar Items