Sequence Diversity in the <italic toggle="yes">pe_pgrs</italic> Genes of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Is Independent of Human T Cell Recognition

ABSTRACT The Mycobacterium tuberculosis genome includes the large family of pe_pgrs genes, whose functions are unknown. Because of precedents in other pathogens in which gene families showing high sequence variation are involved in antigenic variation, a similar role has been proposed for the pe_pgr...

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Bibliographic Details
Main Authors: Richard Copin, Mireia Coscollá, Salome N. Seiffert, Graham Bothamley, Jayne Sutherland, Georgetta Mbayo, Sebastien Gagneux, Joel D. Ernst
Format: Article
Language:English
Published: American Society for Microbiology 2014-02-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00960-13