Mutations in a P-type ATPase gene cause axonal degeneration.

Mutations in a P-type ATPase gene cause axonal degeneration.

Neuronal loss and axonal degeneration are important pathological features of many neurodegenerative diseases. The molecular mechanisms underlying the majority of axonal degeneration conditions remain unknown. To better understand axonal degeneration, we studied a mouse mutant wabbler-lethal (wl). Wa...

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Bibliographic Details
Main Authors: Xianjun Zhu, Richard T Libby, Wilhelmine N de Vries, Richard S Smith, Dana L Wright, Roderick T Bronson, Kevin L Seburn, Simon W M John
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3415440?pdf=render

Internet

http://europepmc.org/articles/PMC3415440?pdf=render

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