Epigenetic-related gene mutations serve as potential biomarkers for immune checkpoint inhibitors in microsatellite-stable colorectal cancer

Epigenetic-related gene mutations serve as potential biomarkers for immune checkpoint inhibitors in microsatellite-stable colorectal cancer

BackgroundCombination therapy with immune checkpoint inhibitors (ICIs) may benefit approximately 10-20% of microsatellite-stable colorectal cancer (MSS-CRC) patients. However, there is a lack of optimal biomarkers. This study aims to understand the predictive value of epigenetic-related gene mutatio...

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Bibliographic Details
Main Authors:	Chao Liu, Huiting Xiao, Luying Cui, Lin Fang, Shuling Han, Yuli Ruan, Wenyuan Zhao, Yanqiao Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Series:	Frontiers in Immunology
Subjects:	immune checkpoint inhibitor therapy biomarker microsatellite-stable colorectal cancer epigenetic-related gene mutations
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1039631/full

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