PROC Promoter Single Nucleotide Polymorphisms Associated With Low Protein C Activity But Not Increased Risk of Thromboembolism in Pediatric Population

Protein C (PC) deficiency, caused by mutations of the PROC gene, is a common inherited risk factor of thromboembolism (TE) among Thai people. This study aimed to investigate the association of 3 single nucleotide polymorphisms (SNPs; −1654 C/T, −1641 A/G, −1461A/T) at the PROC promoter region with P...

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Main Authors: Natsumon Udomkittivorakul MD, Werasak Sasanakul BSc, Jakris Eu-ahsunthornwattana MD, PhD, Ampaiwan Chuansumrit MD, Patcharee Komwilaisak MD, Duantida Songdej MD, PhD, Nongnuch Sirachainan MD
Format: Article
Language:English
Published: SAGE Publishing 2020-06-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/1076029620935206