Functional analysis and validation of oncodrive gene AP3S1 in ovarian cancer through filtering of mutation data from whole-exome sequencing

Functional analysis and validation of oncodrive gene AP3S1 in ovarian cancer through filtering of mutation data from whole-exome sequencing

Abstract Background High-grade serous ovarian carcinoma (HGSOC) is the most aggressive and prevalent subtype of ovarian cancer and accounts for a significant portion of ovarian cancer-related deaths worldwide. Despite advancements in cancer treatment, the overall survival rate for HGSOC patients rem...

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Detaylı Bibliyografya
Asıl Yazarlar: Deshui Kong, Yu Wu, Qiyu Liu, Cuiyu Huang, Tongxia Wang, Zongyao Huang, Yan Gao, Yuan Li, Hongyan Guo
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: BMC 2024-04-01
Seri Bilgileri:European Journal of Medical Research
Konular:
Ovarian cancer
Somatic mutation
AP3S1
Immune infiltration
TGF-β pathway
EMT
Online Erişim:https://doi.org/10.1186/s40001-024-01814-7

Internet

https://doi.org/10.1186/s40001-024-01814-7

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