Protection against Marburg Virus and Sudan Virus in NHP by an Adenovector-Based Trivalent Vaccine Regimen Is Correlated to Humoral Immune Response Levels

Protection against Marburg Virus and Sudan Virus in NHP by an Adenovector-Based Trivalent Vaccine Regimen Is Correlated to Humoral Immune Response Levels

The Marburg virus (MARV) and Sudan virus (SUDV) belong to the filovirus family. The sporadic human outbreaks occur mostly in Africa and are characterized by an aggressive disease course with high mortality. The first case of Marburg virus disease in Guinea in 2021, together with the increased freque...

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Bibliographic Details
Main Authors: Machteld M. Tiemessen, Laura Solforosi, Liesbeth Dekking, Dominika Czapska-Casey, Jan Serroyen, Nancy J. Sullivan, Ariane Volkmann, Maria Grazia Pau, Benoit Callendret, Hanneke Schuitemaker, Kerstin Luhn, Roland Zahn, Ramon Roozendaal
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Vaccines
Subjects:
Ebola virus
Marburg virus
Sudan virus
filovirus
vaccine
Ad26
Online Access:https://www.mdpi.com/2076-393X/10/8/1263

Internet

https://www.mdpi.com/2076-393X/10/8/1263

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