Spatial distribution of elements during osteoarthritis disease progression using synchrotron X-ray fluorescence microscopy

Abstract The osteochondral interface is a thin layer that connects hyaline cartilage to subchondral bone. Subcellular elemental distribution can be visualised using synchrotron X-ray fluorescence microscopy (SR-XFM) (1 μm). This study aims to determine the relationship between elemental distribution...

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Bibliographic Details
Main Authors: Xiwei Fan, Kah Meng Lee, Michael W. M. Jones, Daryl Howard, Antonia Rujia Sun, Ross Crawford, Indira Prasadam
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36911-w