Inferior and medial temporal tau and cortical amyloid are associated with daily functional impairment in Alzheimer’s disease

Inferior and medial temporal tau and cortical amyloid are associated with daily functional impairment in Alzheimer’s disease

Abstract Background A decline in instrumental activities of daily living (IADL) correlates with the progression from mild cognitive impairment (MCI) to Alzheimer’s disease (AD) dementia and has been associated with frontal and parietal hypometabolism, lower cerebrospinal fluid amyloid β 1–42, and in...

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Bibliographic Details
Main Authors: Omar A. Halawa, Jennifer R. Gatchel, Rebecca E. Amariglio, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Gad A. Marshall, Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Instrumental activities of daily living
Tau
Amyloid
Positron emission tomography
Mild cognitive impairment
Online Access:http://link.springer.com/article/10.1186/s13195-019-0471-6

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http://link.springer.com/article/10.1186/s13195-019-0471-6

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