A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor.

Parasites of the phylum Apicomplexa cause diseases that impact global health and economy. These unicellular eukaryotes possess a relict plastid, the apicoplast, which is an essential organelle and a validated drug target. However, much of its biology remains poorly understood, in particular its elab...

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Bibliographic Details
Main Authors: Lilach Sheiner, Jessica L Demerly, Nicole Poulsen, Wandy L Beatty, Olivier Lucas, Michael S Behnke, Michael W White, Boris Striepen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3228799?pdf=render