An inherited FGFR2 mutation increased osteogenesis gene expression and result in Crouzon syndrome

An inherited FGFR2 mutation increased osteogenesis gene expression and result in Crouzon syndrome

Abstract Background FGFR2 encodes a fibroblast growth factor receptor whose mutations are responsible for the Crouzon syndrome, involving craniosynostosis and facial dysostosis with shallow orbits. However, few reports are available quantifying the orbital volume of Crouzon syndrome and there was li...

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Bibliographic Details
Main Authors: Jiayan Fan, Yinwei Li, Renbing Jia, Xianqun Fan
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Medical Genetics
Subjects:
Crouzon syndrome
FGFR2
Orbital volume
Osteoblast genes
Online Access:http://link.springer.com/article/10.1186/s12881-018-0607-8

Internet

http://link.springer.com/article/10.1186/s12881-018-0607-8

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