Flavonoids Enhance Lipofection Efficiency and Ameliorate Cytotoxicity in Colon26 and HepG2 Cells via Oxidative Stress Regulation

Flavonoids Enhance Lipofection Efficiency and Ameliorate Cytotoxicity in Colon26 and HepG2 Cells via Oxidative Stress Regulation

The generation of reactive oxygen species (ROS) can affect cationic liposome-mediated transfection. In this study, we focused on a specific class of antioxidants, flavonoids, to investigate the transfection efficiency using cationic liposome/plasmid DNA complexes (lipoplexes) in 2D and 3D cultures o...

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Bibliographic Details
Main Authors: Die Hu, Shintaro Fumoto, Hirotaka Miyamoto, Masakazu Tanaka, Koyo Nishida
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
lipoplexes
antioxidants
reactive oxygen species
transfection
cell viability
Online Access:https://www.mdpi.com/1999-4923/14/6/1203

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https://www.mdpi.com/1999-4923/14/6/1203

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