Cardiac ryanodine receptor distribution is dynamic and changed by auxiliary proteins and post-translational modification

Cardiac ryanodine receptor distribution is dynamic and changed by auxiliary proteins and post-translational modification

The effects of the immunophilins, FKBP12 and FKBP12.6, and phosphorylation on type II ryanodine receptor (RyR2) arrangement and function were examined using correlation microscopy (line scan confocal imaging of Ca2+ sparks and dual-tilt electron tomography) and dSTORM imaging of permeabilized Wistar...

Full description

Bibliographic Details
Main Authors: Parisa Asghari, David RL Scriven, Myles Ng, Pankaj Panwar, Keng C Chou, Filip van Petegem, Edwin DW Moore
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
ryanodine receptor
excitation-contraction coupling
immunophilins
3D electron tomography
superresolution microscopy
Online Access:https://elifesciences.org/articles/51602

Internet

https://elifesciences.org/articles/51602

Similar Items