Application of topical gentamicin ointment in the treatment of Nagashima‐type palmoplantar keratosis in children with a nonsense mutation

Application of topical gentamicin ointment in the treatment of Nagashima‐type palmoplantar keratosis in children with a nonsense mutation

ABSTRACT Importance Nagashima‐type palmoplantar keratosis (NPPK) is a hereditary dermatosis mostly caused by a nonsense mutation in SERPINB7. Despite the increasing interest in readthrough gentamicin treatment of NPPK, clinical evidence for this treatment is limited. Objective This study aimed to pr...

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Bibliographic Details
Main Authors: Shan Wang, Zhou Yang, Ying Liu, Huan Zhang, Zongyang Liu, Xiaoling Wang, Ying Li, Haihong Liu, Yonghong Yang, Lin Ma
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Pediatric Investigation
Subjects:
Children
Gentamicin
Nagashima‐type palmoplantar keratosis
Nonsense mutation
Readthrough treatment
Online Access:https://doi.org/10.1002/ped4.12389

Internet

https://doi.org/10.1002/ped4.12389

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