Low back pain patients with Modic type 1 changes exhibit distinct bacterial and non-bacterial subtypes

Low back pain patients with Modic type 1 changes exhibit distinct bacterial and non-bacterial subtypes

Objectives: Modic type 1 changes (MC1) are vertebral endplate bone marrow (BM) lesions observed on magnetic resonance images in sub-populations of chronic low back pain (CLBP) patients. The etiopathogenesis remains unknown and treatments that modify the underlying pathomechanisms do not exist. We hy...

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Bibliographic Details
Main Authors: I. Heggli, T. Mengis, C.J. Laux, L. Opitz, N. Herger, D. Menghini, R. Schuepbach, N.A. Farshad-Amacker, F. Brunner, A.J. Fields, M. Farshad, O. Distler, S. Dudli
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Low back pain
Modic changes
Etiology
Cutibacterium acnes
Autoimmunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913124000013

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http://www.sciencedirect.com/science/article/pii/S2665913124000013

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