Generation of SST-P2A-mCherry reporter human embryonic stem cell line using the CRISPR/Cas9 system (WAe001-A-2C)

Somatostatin (SST)-producing pancreatic delta-cells play an important role in maintaining the balance of insulin and glucagon secretion within the islets. This study aimed to generate a human embryonic stem cell (hESC) line with a SST-P2A-mCherry reporter using CRISPR/Cas9 system. The SST-P2A-mCherr...

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Bibliographic Details
Main Authors: Tongran Zhang, Feng Zhang, Nannan Wang, Tao Xu, Lingqiang Zhu, Lihua Chen, Huisheng Liu
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506124000953