Mechanism of Astragaloside Ⅳ on HepG2 Cells Based on Molecular Dynamics Simulation and Experimental Evaluation

Mechanism of Astragaloside Ⅳ on HepG2 Cells Based on Molecular Dynamics Simulation and Experimental Evaluation

Objective To reveal the mechanism of action of AS-Ⅳ on HepG2 cells based on molecular dynamics simulation and experimental evaluation. Methods We constructed a "drug-disease" network pharmacological map, analyzed the core genes of astragaloside Ⅳ (AS-Ⅳ) in HCC, screened key signaling pathw...

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Bibliographic Details
Main Authors: ZHOU Zhipeng, YANG Mingzhu, CAI Mingqin, XUE Juandi, LYU Xiaoyun
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2022-07-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
hepatocellular carcinoma
astragaloside ⅳ
molecular dynamics simulation
vegfa
Online Access:http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.21.1537

Internet

http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.21.1537

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