Trim25 restricts rabies virus replication by destabilizing phosphoprotein
Tripartite motif-containing protein 25 (Trim25) is an E3 ubiquitin ligase that activates retinoid acid-inducible gene I (RIG-I) and promotes the antiviral interferon response. Recent studies have shown that Trim25 can bind and degrade viral proteins, suggesting a different mechanism of Trim25 on its...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-10-01
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Series: | Cell Insight |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772892722000542 |