Trim25 restricts rabies virus replication by destabilizing phosphoprotein

Tripartite motif-containing protein 25 (Trim25) is an E3 ubiquitin ligase that activates retinoid acid-inducible gene I (RIG-I) and promotes the antiviral interferon response. Recent studies have shown that Trim25 can bind and degrade viral proteins, suggesting a different mechanism of Trim25 on its...

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Bibliographic Details
Main Authors: Yueming Yuan, An Fang, Zongmei Wang, Bin Tian, Yuan Zhang, Baokun Sui, Zhaochen Luo, Yingying Li, Ming Zhou, Huanchun Chen, Zhen F. Fu, Ling Zhao
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Cell Insight
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772892722000542