Diazepam and ethanol differently modulate neuronal activity in organotypic cortical cultures

Diazepam and ethanol differently modulate neuronal activity in organotypic cortical cultures

Abstract Background The pharmacodynamic results of diazepam and ethanol administration are similar, in that each can mediate amnestic and sedative-hypnotic effects. Although each of these molecules effectively reduce the activity of central neurons, diazepam does so through modulation of a more spec...

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Bibliographic Details
Main Authors: Matthias Kreuzer, Paul S. García, Verena Brucklacher-Waldert, Rebecca Claassen, Gerhard Schneider, Bernd Antkowiak, Berthold Drexler
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Neuroscience
Subjects:
Diazepam
Ethanol
GABAA receptors
Benzodiazepines
Neocortex
Online Access:https://doi.org/10.1186/s12868-019-0540-6

Internet

https://doi.org/10.1186/s12868-019-0540-6

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