The Complex of p-Tyr42 RhoA and p-p65/RelA in Response to LPS Regulates the Expression of Phosphoglycerate Kinase 1

The Complex of p-Tyr42 RhoA and p-p65/RelA in Response to LPS Regulates the Expression of Phosphoglycerate Kinase 1

Inflammation plays a crucial role in tumorigenesis, primarily mediated by NF-κB. RhoA GTPases are instrumental in regulating the activation of NF-κB. Specifically, the phosphorylation of Tyrosine 42 on RhoA ensures the activation of NF-κB by directly activating the IKKβ associated with IKKγ (NEMO)....

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Detalles Bibliográficos
Autores principales: Oyungerel Dogsom, Amir Hamza, Shohel Mahmud, Jung-Ki Min, Yoon-Beom Lee, Jae-Bong Park
Formato: Artículo
Lenguaje:English
Publicado: MDPI AG 2023-12-01
Colección:Antioxidants
Materias:
RhoA phosphorylation
NF-κB
PGK1
superoxide
cancer
Acceso en línea:https://www.mdpi.com/2076-3921/12/12/2090

Internet

https://www.mdpi.com/2076-3921/12/12/2090

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