Newly Constructed Network Models of Different WNT Signaling Cascades Applied to Breast Cancer Expression Data.

WNT signaling is a complex process comprising multiple pathways: the canonical β-catenin-dependent pathway and several alternative non-canonical pathways that act in a β-catenin-independent manner. Representing these intricate signaling mechanisms through bioinformatic approaches is challenging. Nev...

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Bibliographic Details
Main Authors: Michaela Bayerlová, Florian Klemm, Frank Kramer, Tobias Pukrop, Tim Beißbarth, Annalen Bleckmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4669165?pdf=render