Comparison of the integrin α4β7 expression pattern of memory T cell subsets in HIV infection and ulcerative colitis.

Comparison of the integrin α4β7 expression pattern of memory T cell subsets in HIV infection and ulcerative colitis.

Anti-α4β7 therapy with vedolizumab (VDZ) has been suggested as possible immune intervention in HIV. Relatively little is known about the α4β7-integrin (α4β7) expression of different T-cell subsets in different anatomical compartments of healthy individuals, patients with HIV or inflammatory bowel di...

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Detalhes bibliográficos
Main Authors: Melanie Wittner, Veronika Schlicker, Jana Libera, Jan-Hendrik Bockmann, Thomas Horvatits, Oliver Seiz, Silke Kummer, Carolin F Manthey, Anja Hüfner, Marcus Kantowski, Thomas Rösch, Olaf Degen, Samuel Huber, Johanna M Eberhard, Julian Schulze Zur Wiesch
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2019-01-01
Colecção:PLoS ONE
Acesso em linha:https://doi.org/10.1371/journal.pone.0220008

Internet

https://doi.org/10.1371/journal.pone.0220008

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