Treatment dependent impact of plasma-derived exosomes from head and neck cancer patients on the epithelial-to-mesenchymal transition

Treatment dependent impact of plasma-derived exosomes from head and neck cancer patients on the epithelial-to-mesenchymal transition

BackgroundEpithelial to mesenchymal transition (EMT) is a key process in carcinogenesis of head and neck squamous cell carcinoma (HNSCC), contributing to tumor invasiveness, distant metastasis, and recurrence. Exosomes are known mediators and regulators of EMT. Here, we analyze the impact of exosome...

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Bibliographic Details
Main Authors: Linda Hofmann, Marie Waizenegger, Ralph Röth, Stefanie Schmitteckert, Daphne Engelhardt, Patrick J. Schuler, Simon Laban, Thomas K. Hoffmann, Cornelia Brunner, Marie-Nicole Theodoraki
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
exosomes
HNSCC
EMT
conventional therapy
recurrence
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1043199/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1043199/full

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