GPCRome-wide analysis of G-protein-coupling diversity using a computational biology approach

Abstract GPCRs are master regulators of cell signaling by transducing extracellular stimuli into the cell via selective coupling to intracellular G-proteins. Here we present a computational analysis of the structural determinants of G-protein-coupling repertoire of experimental and predicted 3D GPCR...

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Bibliographic Details
Main Authors: Marin Matic, Pasquale Miglionico, Manae Tatsumi, Asuka Inoue, Francesco Raimondi
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40045-y