ATAD2 interacts with C/EBPβ to promote esophageal squamous cell carcinoma metastasis via TGF-β1/Smad3 signaling

ATAD2 interacts with C/EBPβ to promote esophageal squamous cell carcinoma metastasis via TGF-β1/Smad3 signaling

Abstract Background Distant metastasis is the leading cause of death for esophageal squamous cell carcinoma (ESCC) with limited treatment options and unsatisfactory effectiveness. Bromodomain (BRD) containing proteins are emerging targets for cancer therapy with promising effects. As a unique member...

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Bibliographic Details
Main Authors: Lian-Jing Cao, Yi-Jun Zhang, Si-Qi Dong, Xi-Zhao Li, Xia-Ting Tong, Dong Chen, Zi-Yi Wu, Xiao-Hui Zheng, Wen-Qiong Xue, Wei-Hua Jia, Jiang-Bo Zhang
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Esophageal squamous cell carcinoma
Metastasis
ATAD2
TGF-β signaling pathway
C/EBPβ
Online Access:https://doi.org/10.1186/s13046-021-01905-x

Internet

https://doi.org/10.1186/s13046-021-01905-x

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