Sciatic nerve stimulation alleviates neuropathic pain and associated neuroinflammation in the dorsal root ganglia in a rodent model

Sciatic nerve stimulation alleviates neuropathic pain and associated neuroinflammation in the dorsal root ganglia in a rodent model

Abstract Background Satellite glial cells (SGCs) in the dorsal root ganglia (DRG) play a pivotal role in the formation of neuropathic pain (NP). Sciatic nerve stimulation (SNS) neuromodulation was reported to alleviate NP and reduce neuroinflammation. However, the mechanisms underlying SNS in the DR...

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Bibliographic Details
Main Authors: Chia-En Wong, Wentai Liu, Chi-Chen Huang, Po-Hsuan Lee, Han-Wei Huang, Yu Chang, Hsin-Tien Lo, Hui-Fang Chen, Li-Chieh Kuo, Jung-Shun Lee
Format: Article
Language:English
Published: BMC 2024-08-01
Series:Journal of Translational Medicine
Subjects:
Macrophage
Neuropathic pain
Satellite glial cell
Sciatic nerve stimulation
Online Access:https://doi.org/10.1186/s12967-024-05573-1

Internet

https://doi.org/10.1186/s12967-024-05573-1

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