A T-Cell Epitope-Based Multi-Epitope Vaccine Designed Using Human HLA Specific T Cell Epitopes Induces a Near-Sterile Immunity against Experimental Visceral Leishmaniasis in Hamsters

Visceral leishmaniasis is a neglected tropical disease affecting 12 million people annually. Even in the second decade of the 21st century, it has remained without an effective vaccine for human use. In the current study, we designed three multiepitope vaccine candidates by the selection of multiple...

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Bibliographic Details
Main Authors: Aryandra Arya, Sunil K. Arora
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/9/10/1058