Regulation of SLC7A11 as an unconventional checkpoint in tumorigenesis through ferroptosis

Although cell-cycle arrest, senescence, and apoptosis are well accepted as the classic barriers in tumorigenesis, recent studies indicate that metabolic regulation is equally important as a major checkpoint in cancer development. It is well accepted that ferroptosis, an iron-dependent programmed cel...

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Bibliographic Details
Main Authors: Zhenyi Su, Yanqing Liu, Lin Wang, Wei Gu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-01-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304224000515