Deficit in hippocampal ripples does not preclude spatial memory formation in APP/PS1 mice
Abstract General theory of declarative memory formation posits a cortical-hippocampal dialog during which hippocampal ripple oscillations support information transfer and long-term consolidation of hippocampus dependent memories. Brain dementia, as Alzheimer disease (AD), is accompanied by memory lo...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-12-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-019-56582-w |