Co-Existence of CYP2C19*1/*2 and ABCB1c.3435 CT Genotype has a Potential Impact on Clinical Outcome in CAD Patients Treated with Clopidogrel

Co-Existence of CYP2C19*1/*2 and ABCB1c.3435 CT Genotype has a Potential Impact on Clinical Outcome in CAD Patients Treated with Clopidogrel

Clopidogrel, is a standard treatment in the prevention of major adverse cardiovascular events (MACE) in patients with coronary artery disease (CAD). Clopidogrel response is highly variable, mainly due to the presence of polymorphisms in the genes involved in drug metabolism. The aim of this study wa...

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Bibliographic Details
Main Authors: Nestorovska KA, Naumovska Z, Staninova Stojovska M, Sterjev Z, Dimovski A, Suturkova Lj
Format: Article
Language:English
Published: Sciendo 2024-03-01
Series:Balkan Journal of Medical Genetics
Subjects:
abcb1
clopidogrel
cyp2c19
coronary artery disease
p-glycoprotein
pharmacogenetics
Online Access:https://doi.org/10.2478/bjmg-2023-0023

Internet

https://doi.org/10.2478/bjmg-2023-0023

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