Potentiating the activity of nisin against Escherichia coli

Lantibiotics are antimicrobial (methyl) lanthionine-containing peptides produced by various Gram-positive bacteria. The model lantibiotic, nisin, binds lipid II in the cell membrane. Additionally, after binding it can insert into the membrane creating a pore. Nisin can efficiently inhibit the growth...

Full description

Bibliographic Details
Main Authors: Liang eZhou, Auke J. van Heel, Manuel eMontalban-Lopez, Oscar P. Kuipers
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00007/full