A simple strategy for reducing false negatives in calling variants from single-cell sequencing data.

Due to the growth of interest in single-cell genomics, computational methods for distinguishing true variants from artifacts are highly desirable. While special attention has been paid to false positives in variant or mutation calling from single-cell sequencing data, an equally important but often...

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Bibliographic Details
Main Authors: Cong Ji, Zong Miao, Xionglei He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395317?pdf=render