Inherited Mutations in DNA Damage Repair Genes in Italian Men with Metastatic Prostate Cancer: Results from the Meet-URO 10 Study

Inherited Mutations in DNA Damage Repair Genes in Italian Men with Metastatic Prostate Cancer: Results from the Meet-URO 10 Study

Background: The prevalence of pathogenic germline mutations in DNA damage repair (gDDR) genes in the Italian population is unknown. Objective: In this prospective multicenter cohort study, we evaluated the prevalence of gDDR alterations in the Italian population affected by metastatic prostate cance...

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Bibliographic Details
Main Authors: Chiara Casadei, Emanuela Scarpi, Vincenza Conteduca, Giorgia Gurioli, Maria Concetta Cursano, Nicole Brighi, Cristian Lolli, Giuseppe Schepisi, Umberto Basso, Giuseppe Fornarini, Sara Bleve, Alberto Farolfi, Amelia Altavilla, Salvatore Luca Burgio, Emilio Francesco Giunta, Caterina Gianni, Alessia Filograna, Paola Ulivi, David Olmos, Elena Castro, Ugo De Giorgi
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:European Urology Open Science
Subjects:
DNA damage repair gene mutations
Germline BRCA2 mutations
Metastatic prostate cancer
Precision medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S266616832400226X

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http://www.sciencedirect.com/science/article/pii/S266616832400226X

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